Natural estrogen levels in a woman’s body decline causing symptoms like hot flashes and mood swings during menopause. Estrogen replacement therapy was recommended to relieve menopausal symptoms, for many years. As the egg supply in the ovaries is depleted, they begin to produce less estrogen and finally shut down completely. Other organs produce estrogen as well, so even after menopause it is still found in the blood stream, just at much lower levels than when a woman was young.
In the 1930 ‘s, scientists recognized that they could isolate the natural estrogen from the urine of pregnant women, but continued to look for other sources, in order to make mass production possible. Researchers learned to create estrogen in the laboratory and isolate it from the urine of pregnant mares during that decade.
Continuing In This Direction..
In the past, the majority of treatment limited the dose to 1.25 mg to 2.5 mg per day. Today, recommended daily dose of.625 Mg, which is necessary in order to achieve the osteoporosis reduction benefit. Most of the risks are small; the patient must weigh the advantages and disadvantages and select whether to continue with the conjugated estrogen or not. Some women deny the treatment because the source of conjugated estrogen is taken from the urine of pregnant mares. Objecting to the practice of keeping mares pregnant for the recovery of estrogen, these women also classify menopause as the natural phenomenon. There are some women reject the use of ERT on principle, disliking the idea of using a synthetic hormone. This disrupts the natural evolution of the body, and fearing past disasters such as occurred with DES.
Another valid point on the topic of estrogen
In 1941, estrogen replacement therapy was adopted by the FDA for the treatment of menopausal symptoms.
And There’s More!
Estrogen replacement therapy was very popular until around 1975 when researchers learned that it could cause endometrial cancer. The endometrium is the lining of the uterus. Natural estrogen produced by the ovaries causes the lining to thicken, preparing for a fertilized egg. During a woman’s reproductive years, if no egg is fertilized, the ovaries produce progesterone. This causes the endometrium to be shed during menstruation. Estrogen replacement therapy caused the lining to thicken, but since progesterone was not present, the lining was not shed, resulting in cancer of the endometrium in many women.
To reduce the risk of endometrial cancer, doctors began to prescribe a combination of progesterone and estrogen replacement for women during menopause. This ‘combination therapy’ was very popular until 2001, when the Women’s Health Initiative found that the health risks associated with this therapy outweighs the benefits. Hormone replacement therapy had been commonly recommended, not only in order to reduce the symptoms of menopause, but likewise to reduce a woman’s risk of colorectal cancer and osteoporosis.
During the five year study, researchers followed groups of women who were using combined hormone replacement therapy, either estrogen replacement only, or a placebo (no HRT at all). Researchers had originally intended to keep up with the women for several more years. However, research was halted due to the number of reported adverse events among women using HRT. The adverse events reported were breast cancer, heart disease, stroke, blood clots, and pulmonary embolism.
The information gathered by the research group indicates that while combination HRT decreases a woman’s risk of endometrial cancer, it increases a woman’s risk of breast cancer. One group of women in the survey was able to use estrogen replacement only, because they had previously had a hysterectomy, thus estrogen posed no threat of endometrial cancer. Researchers concluded that the combination therapy increased a woman’s risk of breast cancer after comparing the number of cases of breast cancer in this estrogen only group to the group using combination HRT. Topically applied hormones, such as natural estrogen creams, aren’t believed to bring the risks of orally administered hormones.
Some brands of HRT are advertised as ‘natural estrogen’ because the origin of the estrogen is natural; mare urine. Some people refer to bio-identical hormones as ‘natural ‘, because they’re designed to be molecularly identical to the natural estrogen and other hormones created by a woman’s body.
Bio-identical hormone replacement therapy is somewhat popular, due in part to a book prepared by a female TV star, who upon entering menopause was unhappy with all that went along with it and found a clinic that offers this kind of treatment. It is more costly and not available from all doctors. Basically, bio-identical HRT involves creating hormones in the laboratory that are structurally identical to a woman’s own hormones. Compounding pharmacists use plant estrogens from yams and soy, as well as animal estrogens from horses and pigs and ‘adjust’ them, so that they’re so similar to those produced by the human body, that, theoretically, the body can not tell the difference. To date, no studies have been carried out concerning the health risks associated with the long run use of bio-identical HRT.
Thus the primary purpose of taking hormone replacement therapy is to restore what nature and time has depleted. It therfore involves replinishing the woman’s body with external hormones or estrogens. Women suffering from hormonal disturbences are prescribed estrogens derived from horse urine since these are very close to the human estrogens since the discovery of hormone replacement therapy.
These estrogens are horse estrogens and therefore foreign to the body and involve many serious side effects despite being similar to human estrogens. Esnatri is a triple estrogen cream and is seen as a breakthrough in hormone replacement therapy for women.
It is a natural estrogen cream which is made made up synthetic hormones which are similar to human hormone estrogens and developed in the same ratio as observed in the human body. Esnatri thus is called as a natural estrogen cream which offers a safer and more efficient alternative to hormone replacement therapy using horse hormones.
The three estrogens are estriol, estradiol and estrone. While most conventional estrogen creams available in tha market contain these hormones in the ratio 80:10:10, this natural estrogen cream, Esnatri a unique, because it contains natural synthetically prepared human estrogens of 90% estriol, 3% estrone, and 7% estradiol. These amounts are deemed to be the closest to the natural female levels.
Rather than offering the quick fix of estrogen replacement or other types of HRT, some of the most beautiful women’s clinics begin treatment by counseling women about diet, nutrition, dietary, and lifestyle supplements. In many cases, making healthy changes in lifestyle and diet and adding nutritional supplements helps to increase a woman’s natural estrogen levels, relieves menopausal symptoms and makes HRT unnecessary. To learn more, please visit the Menopause and PMS Guide.